Repositive hires pioneer of personal genomics Manuel Corpas

Please welcome the newest member of the Repositive family: Manuel Corpas. Manuel is joining Repositive as Scientific Lead on September 1st and brings with him not only a wealth of experience, but also a passion for open science and collaboration within the scientific community.

Manuel has extensively studied bioinformatics, computational biology and biomedical sciences for over 12 years, in both the UK and Spain. He also spent several months as a visiting scholar in the United States: at the Supercomputer Centre in San Diego and at the Virginia Bioinformatics Institute.

Project Leader

Manuel's dedicated studies projected him into a successful career, culminating as Project Leader for Plant and Animal Genomes at TGAC (The Genome Analysis Centre), a position he held for over 4 years before joining Repositive. Manuel has several years' experience utilising genomics data for research purposes. As Project Leader at TGAC, he was leading a group of computational biologists who were responsible for organising the analysis of sequencing data generated by TGAC and engaging with collaborators on the analysis of genomic data.

Bioinformatics

Manuel is also uniquely experienced to support the future developments of the Repositive platform by utilising over 3 years' experience as a Senior Developer for the Wellcome Trust Sanger Institute. During this time he helped develop DECIPHER, a powerful web-based database for clinical diagnosis and management of patients with congenital abnormalities. DECIPHER provided tools to help in interpretation of copy number changes in patients with developmental disorders.

Dig only a little big deeper into Manuel's career and you will also find that he worked at EBI as a Scientific Programmer, in which he set up a systems biology database called EnDICTION, for integration of computer generated predictions from the ENFIN Network of Excellence.

It is also important to mention that Manuel is the instigator and coordinator running the BioJS community and is a board director of the International Society for Computational Biology (ISCB).

Pioneer of Personal Genomics

If Manuel's experience and education was not enough to demonstrate his unique fitting with the Repositive mission and values, a simple visit to his blog should remedy that. In 2012, Manuel embarked on an incredible journey after sending off his DNA to be sequenced by 23andMe, which ultimately lead to Manuel organising the sequencing of his entire family.

You may be thinking "how does this make Manuel a pioneer?" Well, Manuel was among the few who not only documented the entire journey from receiving kits in the post to analysing the data. But he was the first to publish online as Open Access the entire collection of genomic data from himself and his family: the Corpasome1. The Corpasome data collection includes 23andMe genotyping data that was annotated using SNPedia, BGI whole exome sequencing data that was aligned using InSilicoDB, and BGI faecal metagenomics data.

Manuel did not stop his journey there - he made a public call for participation for the analysis of his genome data and international experts in genome analysis collaborated with Manuel to create the first ever crowd-sourced analysis of Manuel Corpas and his family's genomes. His publication on this analysis became among the BMC top influential articles in 2015: https://manuelcorpas.com/2016/04/11/article-crowdsourced-analysis-of-family-genome-among-bmc-genomics-most-influential-articles-for-2015/

So, as well as contributing his skills and experience to Repositive to enable us to better serve the scientific community, he has gone above and beyond by contributing his own genome.

You will be hearing more from Manuel and his work for Repositive, as he kicks off a series of workshops from September 2016.

References

  1. Manuel Corpas, Willy Valdivia-Granda†, Nazareth Torres†, Bastian Greshake†, Alain Coletta, et al. Crowdsourced direct-to-consumer genomic analysis of a family quartet. BMC Genomics. 2015. 16:910. DOI: 10.1186/s12864-015-1973-7


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More information about the hiring of Manuel Corpas can be found on our press release.

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